2B or not 2B, that is the question: further investigations into the use of pencil as a matrix for matrix-assisted laser desorption/ionisation.

Matrix-suppressed laser desorption/ionisation mass spectrometry and its suitability for metabolome analyses.

Matrix-assisted laser desorption/ionisation (MALDI) mass spectrometry was investigated for the simultaneous detection of several metabolites, as applicable to global metabolite analysis (metabolomics). The commonly employed organic matrices alpha-cyano-4-hydroxycinnamic acid and 3,5-dihydroxybenzoic acid, in both the crystalline and ionic liquid forms, were investigated. The employment of a low...

Characterisation of bacteria by matrix-assisted laser desorption/ionisation and electrospray mass spectrometry.

Chemical analysis for the characterisation of micro-organisms is rapidly evolving, after the recent advent of new ionisation methods in mass spectrometry (MS): electrospray (ES) and matrix-assisted laser desorption/ionisation (MALDI). These methods allow quick characterisation of micro-organisms, either directly or after minimum sample preparation. This review provides a brief introduction to E...

ABCD matrix for reflection and refraction of laser beam at tilted concave and convex elliptic paraboloid interfaces and studying laser beam reflection from a tilted concave parabola of revolution

Studying Gaussian beam is a method to investigate laser beam propagation and ABCD matrix is a fast and simple method to simulate Gaussian beam propagation in different mediums. Of the ABCD matrices studied so far, reflection and refraction matrices at various surfaces have attracted a lot of researches. However in previous work the incident beam and the principle axis of surface are in parallel...

Matrix-free mass spectrometric imaging using laser desorption ionisation Fourier transform ion cyclotron resonance mass spectrometry

Mass spectrometry imaging (MSI) is a powerful tool in metabolomics and proteomics for the spatial localization and identification of pharmaceuticals, metabolites, lipids, peptides and proteins in biological tissues. However, sample preparation remains a crucial variable in obtaining the most accurate distributions. Common washing steps used to remove salts, and solvent-based matrix application,...

Rapid Identification of Anaerobic Bacteria Using Matrix Assisted Laser Desorption Ionisation Time-of-flight Mass Spectrometry